By Brian Winkel


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We ask students to build differential equations to model lysergic acid diethylamide (LSD) in the body. We provide the data from the literature. We offer students the opportunity to build a model to fully analyze the administration and absorption of LSD in 8 student volunteers. We also compare the model predictions with data from the experimental study on problem-solving performance on simple arithmetic activities given to subjects over the time of distribution and absorption of the LSD.

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Researchers should cite this work as follows:

  • Brian Winkel (2015), "1-010-S-LSDAndProblemSolving," https://www.simiode.org/resources/411.

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